I would definitely go for it, the only thought that occurs is that if
you want to any decorative rather than functional quilting that it would
be rather like doing machine embroidery and need a stabiliser. If you
needed to do that over the entire quilt that could end up expensive, but
if there are just sections you want to pay more attention to, it would
probably work out fine you could just iron on some tear away stabiliser
under those sections.

cheers
Anne